Michele Danilo Pierri 
Upgrading a local AI workstation from an RTX 3060 12GB to an RTX 3090 24GB with real-world LLM, Flux and Whisper benchmarks. Article authored by Michele D. Pierri, MD Cardiac Surgeon & Medical Technology Researcher Last checked: June 10, 2026 Reading time: 5 minutes There are days when you don’t go to the operating room. … Read more
From passive Q&A to autonomous agents that debate, challenge, and assist clinicians. Article authored by Michele D. Pierri, MD Cardiac Surgeon & Medical Technology Researcher Last updated: June 2026 Reading time: 15 minutes Key takeaways 1. Redefining AI in Medicine: What Is an Agentic System? The first wave of AI in healthcare gave us chatbots. … Read more
I am a cardiac surgeon. My work is rooted in the operating room, in clinical decisions, and in the care of individual patients. At the same time, I have become deeply interested in medical data, statistics, coding, and artificial intelligence. My fascination with the history of medicine, however, has remained just as strong. At first … Read more
Machine Learning and Large Language Models for Clinical Text Analysis Article authored by Michele D. Pierri, MD Cardiac Surgeon & Medical Technology Researcher Last updated: May 2025 Reading time: 30 minutes Abstract The first two articles in this series traced a progression from rule-based pattern matching (regular expressions) to linguistic analysis (spaCy/scispaCy) for extracting structured … Read more
Non-Parametric Statistics in Medicine: A Practical Guide for Skewed, Ordinal, and Small Clinical Datasets Last updated: May 2026 Author: Michele D. Pierri Reading time: 15–20 minutes Introduction Clinical data rarely behave like the textbook examples we encounter in introductory statistics courses. Length of stay tends to be right-skewed. Biomarkers such as C-reactive protein, ferritin, D-dimer, … Read more
Introduction to Natural Language Processing for Medical Report Analysis: Advanced Linguistic Analysis with spaCy and scispaCy for Medical Reports Article authored by Michele D. Pierri, MD Cardiac Surgeon & Medical Technology Researcher Last updated: May 2025 Reading time: 30 minutes Abstract Regular expressions give us a solid foundation for pulling structured data out of clinical … Read more
Doctor Zhivago turns the daily work of a physician into a lens for what care becomes when institutions break. War medicine, infectious disease, rural scarcity. Through these threads Pasternak delivers a lesson that still cuts close to contemporary, technology-driven healthcare: clinical judgment and ethical independence carry the most weight precisely when the system around them … Read more
ChatGPT for Clinicians: A First Look from Italy Article authored by Michele D. Pierri, MD Cardiac Surgeon & Medical Technology Researcher Last checked: April 28, 2026 Reading time: 7 minutes OpenAI has rolled out a set of healthcare-oriented products built around ChatGPT. The headline reads, at first, like the launch of a single “medical GPT” … Read more
Part 4: the conclusion of the “Local AI” series — The LM Studio surprise: same model, same hardware, 40-200x faster In Part 3, we pushed gemma4:e4b through four demanding tests. The results were impressive — excellent clinical reasoning, comprehensive summaries, working code. But the wait times were brutal: 5 to 16 minutes per response on … Read more
Part 3 of the “Local AI” series — Coding, reasoning, medical summarization, and clinical decision support Benchmarks tell you how fast a model runs. They don’t tell you if it can actually do anything useful. In Part 1 we set up Ollama, and in Part 2 we measured generation speeds. Now we push these models … Read more