Notes, research and personal trajectories
Mais il est aussi de ceux qu'on peut comparer aux arbres parce que leur croissance obéit, non pas comme celle des constructions humaines, à une loi de l'addition de chaque jour et de chaque instant, mais à une force intérieure qui dépose, d'après un plan caché, au-dedans des anciens dépôts, des couches nouvelles.
But he is also one of those who may be compared to trees, because their growth obeys not, like that of human constructions, a law of daily and moment-by-moment addition, but an inner force which, according to a hidden design, lays new layers within the old deposits.
Marcel Proust, Le Temps retrouvé
I am a cardiac surgeon. My work is rooted in the operating room, in clinical decisions, and in the care of individual patients. At the same time, I have become deeply interested in medical data, statistics, coding, and artificial intelligence. My fascination with the history of medicine, however, has remained just as strong. At first...
There is a specific moment, familiar to anyone who has gone down this road, when you finish downloading a model with “Med” in its name and realise you have no idea whether it is actually any good. The name promises domain expertise. The model card promises benchmarks. Neither tells you what happens when you ask...
Non-inferiority Trials in Medicine: Last updated: June 2026 Author: Michele D. Pierri Reading time: 15–20 minutes In clinical research, we are used to thinking that a new drug, device, or procedure should be tested by asking a simple question: Is it better than what we already have? This is the logic of a superiority trial....
A reproducible 300-question evaluation across medical exams, biomedical literature, multilingual question answering, and clinical calculation Meta released Muse Glimmer on 10 August 2026: thirty billion parameters, open weights, built for agentic work on consumer hardware.[1,2] I tested a quantized version five days later on a single NVIDIA RTX 3090 — partly because it was the...
Vasoactive-Inotropic Score as a Worked Example Introduction: The Data Is There. The Variable Is Not. Every conversation about clinical AI opens on the same premise: hospitals are sitting on enormous quantities of data. True enough, and almost useless as a starting point. An electronic health record is a transactional system, built for documentation, for billing,...
Narrative medicine transforms clinical practice through close reading and reflective writing. A comprehensive guide for physicians and researchers, from Rita Charon's Columbia programme to Oliver Sacks, Tolstoy, and Jerome Groopman.
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