micheledpierri.com: statistics, data analysis and coding
Nexus of Statistics, Data analysis, Coding, Art and Medicine
Non-inferiority Trials in Medicine: Last updated: June 2026 Author: Michele D. Pierri Reading time: 15–20 minutes In clinical research, we are used to thinking that a new drug, device, or procedure should be tested by asking a simple question: Is it better than what we already have? This is the logic of a superiority trial….
Upgrading a local AI workstation from an RTX 3060 12GB to an RTX 3090 24GB with real-world LLM, Flux and Whisper benchmarks. Article authored by Michele D. Pierri, MD Cardiac Surgeon & Medical Technology Researcher Last checked: June 10, 2026 Reading time: 5 minutes There are days when you don’t go to the operating room….
From passive Q&A to autonomous agents that debate, challenge, and assist clinicians. Article authored by Michele D. Pierri, MD Cardiac Surgeon & Medical Technology Researcher Last updated: June 2026 Reading time: 15 minutes Key takeaways 1. Redefining AI in Medicine: What Is an Agentic System? The first wave of AI in healthcare gave us chatbots….
I am a cardiac surgeon. My work is rooted in the operating room, in clinical decisions, and in the care of individual patients. At the same time, I have become deeply interested in medical data, statistics, coding, and artificial intelligence. My fascination with the history of medicine, however, has remained just as strong. At first…
Machine Learning and Large Language Models for Clinical Text Analysis Article authored by Michele D. Pierri, MD Cardiac Surgeon & Medical Technology Researcher Last updated: May 2025 Reading time: 30 minutes Abstract The first two articles in this series traced a progression from rule-based pattern matching (regular expressions) to linguistic analysis (spaCy/scispaCy) for extracting structured…
Non-Parametric Statistics in Medicine: A Practical Guide for Skewed, Ordinal, and Small Clinical Datasets Last updated: May 2026 Author: Michele D. Pierri Reading time: 15–20 minutes Introduction Clinical data rarely behave like the textbook examples we encounter in introductory statistics courses. Length of stay tends to be right-skewed. Biomarkers such as C-reactive protein, ferritin, D-dimer,…
Introduction to Natural Language Processing for Medical Report Analysis: Advanced Linguistic Analysis with spaCy and scispaCy for Medical Reports Article authored by Michele D. Pierri, MD Cardiac Surgeon & Medical Technology Researcher Last updated: May 2025 Reading time: 30 minutes Abstract Regular expressions give us a solid foundation for pulling structured data out of clinical…
Doctor Zhivago turns the daily work of a physician into a lens for what care becomes when institutions break. War medicine, infectious disease, rural scarcity. Through these threads Pasternak delivers a lesson that still cuts close to contemporary, technology-driven healthcare: clinical judgment and ethical independence carry the most weight precisely when the system around them…
ChatGPT for Clinicians: A First Look from Italy Article authored by Michele D. Pierri, MD Cardiac Surgeon & Medical Technology Researcher Last checked: April 28, 2026 Reading time: 7 minutes OpenAI has rolled out a set of healthcare-oriented products built around ChatGPT. The headline reads, at first, like the launch of a single “medical GPT”…
Part 4: the conclusion of the “Local AI” series — The LM Studio surprise: same model, same hardware, 40-200x faster In Part 3, we pushed gemma4:e4b through four demanding tests. The results were impressive — excellent clinical reasoning, comprehensive summaries, working code. But the wait times were brutal: 5 to 16 minutes per response on…